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InsideResearchSummer2019FINALONLINE
LISTING OF ALL THE NEWS FROM RESEARCH THROUGHOUT THE INSTITUTION:
brain cell image

Los Angeles Times - Scientists have found that the coronavirus that causes COVID-19 is capable of infecting two types of brain cells — neurons and astrocytes. Scientists have been trying to understand why and how it causes these issues in the brain, said study leader Diana Cruz-Topete, a molecular endocrinologist at LSU Health Shreveport.

Read More about Scientists see path for the coronavirus to invade the brain (opens in new window/tab)
New Faculty Spotlight - Dr. Changwon Park

Associate Professor, Dr. Changwon Park is a new addition to the Department of Molecular and Cellular Physiology. The major effort of his lab is to decipher the underlying cellular and molecular mechanisms as to the successful generation of the cardiovascular constituents, namely endothelial, endocardium, cardiomyocytes, and hematopoietic cells that share the multipotent cardiovascular progenitors, FLK1 (also known as VEGFR2) expressing cells.

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COVID Variant Hunter: Even Vaccinated Should Keep Wearing Masks

NBC CT - LSU Health Shreveport Virologist Jeremy Kamil told NBC Connecticut Investigates that halting their spread will require other measures. Kamil was among a team of researchers that discovered seven new COVID-19 strains, known as "variants," aside from the variants first identified in the UK, South Africa, and Brazil. 

Read More about COVID Variant Hunter: Even Vaccinated Should Keep Wearing Masks (opens in new window/tab)
Dr. Xiao-Hong Lu looks through microscope in lab

Dr. Xiao-Hong Lu’s research team will use the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory to simulate cosmic radiation in space vehicles and on the Martian surface to determine if long-term exposure to radiation causes adverse consequences to the brain.

Read More about Xiao-Hong Lu PhD, LSU Health Shreveport researcher receives $750K grant from NASA (opens in new window/tab)
The vaccines are working. That's why we shouldn't panic about variants.

NBC News - "There are certain variants that are more transmissible, and we have strong data on that, but the thing people should take away from the variant story is just: Don't let your guard down," said Dr. Jeremy Kamil, an associate professor of microbiology and immunology at Louisiana State University Health Shreveport.

Read More about The vaccines are working. That's why we shouldn't panic about variants. (opens in new window/tab)
COVID-19 variants

KTBS3 -  A researcher at LSU Health Shreveport has co-authored a study about seven new variants of the COVID-19 virus that appear to have originated in the U.S. The variants appear to have originated in the U.S. But Jeremy Kamil, associate professor of microbiology and immunology at LSUHS, said it is not a cause for panic.

Read More about LSU Health Shreveport researcher discovers new COVID variants (opens in new window/tab)
Drug, Alcohol, Tobacco Use at a Young Age Can Cause Premature Heart Problems

People who start using substances at a younger age have worse health outcomes over the long term, which requires “a nationwide education campaign on the potential long-term damage being done to the cardiovascular system in patients with substance use disorders,” writes Dr. Anthony Orr, Director of Center of Excellence for Cardiovascular Diseases and Sciences at LSUHS.

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‘We’re in the dark’: The U.S. is way behind on testing for dangerous COVID variants

Fortune.com - Even the type of sequencing done in the U.S. has been lacking, some experts say, with much of the effort focused on finding cases of the U.K. variant, rather than casting a wider net for any variant, including ones not previously identified, said Jeremy Kamil, a virologist at Louisiana State University Health Shreveport.

Read More about ‘We’re in the dark’: The U.S. is way behind on testing for dangerous COVID variants (opens in new window/tab)
scientist in lab

Bloomberg.com - Even the type of sequencing done in the U.S. has been lacking, some experts say, with much of the effort focused on finding cases of the U.K. variant, rather than casting a wider net for any variant, including ones not previously identified, said Jeremy Kamil, a virologist at LSU Health Shreveport. “It’s the Wild West,” he said. “Every state, city, county is doing its own thing. It’s a bunch of random cats and no one is trying to herd them.”

Read More about U.S. Falters in DNA Testing to Detect Dangerous Covid Mutations (opens in new window/tab)
Pfizer-BioNTech COVID-19 vaccine vial

KSLA 12 - Dr. Robert Rhoads, professor and emeritus chairman of the Department of Biochemistry and Molecular Biology at LSU Health Shreveport, developed key components of the mRNA over years of work. The vaccine uses messenger RNA, or mRNA, which essentially provides instructions to the body on how to fight the novel coronavirus.

Read More about Technology developed at LSU Health Shreveport played key role in COVID-19 vaccine development
COVID-19 vaccine arrives at Ochsner-LSU Health Shreveport

KSLA 12 - “It is gratifying to see LSU Health Shreveport’s contributions to the Pfizer-BioNTech vaccine through licensing of a LSUHS patent to BioNTech for mRNA-stabilizing cap analogs and in serving as the only north Louisiana vaccine trial site. Additionally our numerous COVID-19 clinical trials are providing access to novel therapies reflecting the benefit of having an academic medical center in our community,” shared Dr. G.E. Ghali, Chancellor of LSU Health Shreveport.

Read More about COVID-19 vaccine arrives at Ochsner-LSU Health Shreveport
video clip image

KSLA 12- “If the EVT Lab had not existed, quite frankly, I think we’d be in a much darker place here in the northern part of the state,” said Dr. Chris Kevil, vice chancellor of research and one of the leading minds behind creation of the lab. “The EVT Lab has been fundamental in our ability to monitor COVID infections in patients out in this community."

Read More about Amid dark days of pandemic, LSU Health Shreveport’s Emerging Viral Threat Lab stands as a beacon of hope (opens in new window/tab)
Focus Fund and MD Anderson Launch Investment Fund to Support Investigational Cancer Therapies

The Feist-Weiller Cancer Center is excited to be a part of the Cancer Focus Fund to bring the latest new cancer clinical trials to our community," said Dr. Chris Kevil, Vice-Chancellor for Research at LSU Health Shreveport. "We are confident our clinical trial facilities, coupled with expanded patient access to clinical trials across north and central Louisiana in partnership with Ochsner Health, will yield promising results for all citizens of Louisiana.

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LSU Health Shreveport Leads Louisiana  in COVID-19 VIRAL GENOME SEQUENCING

The Emerging Viral Threat (EVT) Lab at LSU Health Shreveport has now sequenced a total 651 Louisiana SARS-CoV-2 virus genomes making them the largest contributor to date of genetic data on SARS-CoV-2 in the state. SARS-CoV-2, which is short for ‘Severe Acute Respiratory Syndrome Coronavirus-2,’ is the virus that causes COVID-19, and viral genome sequencing is contributing to a worldwide effort to fight the ongoing pandemic.

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Dr. Rajib Gupta - LSU Health Shreveport

Dr. Rajib Gupta, shares "COVID-19 is an ongoing pandemic which has affected over 12 million people across the globe. Manifestations in different organs systems are being reported regularly. Renal biopsy findings in hospitalized COVID-19 patients presenting solely with acute kidney injury have recently been described in published literature in few case reports. We describe the kidney biopsy findings of two patients who had recent diagnoses of COVID-19 and presented with new-onset nephrotic syndrome."

Read More about Dr. Rajib Gupta research is featured in BMC Nephrology (opens in new window/tab)
Nobel Prize-Winning Scientist Explains Why New Study in New England Journal of Medicine May Point To Nitric Oxide as Successful Treatment For COVID-19

Keith Scott, MD, MSc, FCCM, Professor and the clinical trial's Principal Investigator for the nitric oxide trials at LSU Health Shreveport says, "Teasing out the influence of naturally produced NO on this process is difficult. What I am very encouraged about is the demonstration of virus in the endothelial cells of the lung tissue."

Read More about Nobel Prize-Winning Scientist Explains Why New Study in New England Journal of Medicine May Point To Nitric Oxide as Successful Treatment For COVID-19 (opens in new window/tab)
News story by WBRZ-2 with update on clinical trials

WBRZ News - “We know a lot of these things work, we just don’t know when they work the best. And that’s what we’re trying to figure out really right now is when, how much and where. And that’s the confusing part of this whole disease. It’s nothing like we’ve ever seen, nothing like medicine has ever seen,” Dr. Keith Scott said.

Read More about Researchers say more time, data will determine if nitric oxide therapy is effective against COVID-19 (opens in new window/tab)
Donating Plasma

MyArkLaMiss.com - Scientists at LSU Health Shreveport continue to have a significant impact on the fight against COVID-19 in Louisiana with their latest achievement being able to offer serology testing to support the Convalescent Plasma Therapy clinical trial and help identify ideal plasma donors.

Read More about LSU Health Shreveport Launches COVID-19 Antibody Testing Capability (opens in new window/tab)
LSU Health Shreveport doctors begin Nitric Oxide trial for COVID-19

“What we’re so excited about is this, it’s FDA approved. Almost any hospital of any size already has a ventilator, already has the gas and if this is something that does work it could start being applied immediately,” said LSUHS Professor, Keith Scott, MD.

Read More about How Nitric Oxide can help coronavirus patients as clinical trial gets underway at LSUHS (opens in new window/tab)
WWL News image of coronavirus

Research from LSU Health Shreveport has shown that nitric oxide is a strong protector against tissue hypoxia. “It’s just really a raging phenomenon that occurs in the lung and if we can just calm that down a little bit and allow the body’s natural systems to come in an heal it, that’s the real goal,” said Scott.

Read More about LSU Health Shreveport testing if inhaled nitric oxide can fight COVID-19 (opens in new window/tab)
Dr. Ghali video about COVID-19 efforts on KTAL News

“Certainly we’ve ramped up our testing,” Dr. G.E. Ghali, LSUHS Chancellor, said. “We’ve increased our capacity by 60 percent right off the bat of number of ICU beds that we have.” The increased testing is thanks to the new Emerging Viral Threat Lab that can provide results in less than 48 hours, freeing resources.

Read More about LSU Health Shreveport ramping up efforts in COVID-19 fight (opens in new window/tab)
Dr. Yurochko in the lab

The Shreveport Times reached out to Professor Andrew Yurochko, Carroll Feist endowed chair of viral oncology and department vice-chair of microbiology and immunology, LSUHS, with the Emerging Viral Threat lab which began processing COVID-19 samples last Wednesday.

Read More about Why are so many people testing positive in Caddo/Bossier? LSUHS Expert provides answers (opens in new window/tab)
Scientists working in lab

Having an academic medical center is a “gem” touted frequently throughout north Louisiana and beyond. While many in the nation are fearful of having appropriate access to testing and quality care during the Covid-19 pandemic, thanks to LSU Health Shreveport, north Louisiana is infinitely better positioned than most communities to face Covid-19.

Read More about LSU Health Shreveport continues mission to Teach, Heal and Discover

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