LSU Health Shreveport is now one of five sites in the world and the first in Louisiana involved in a clinical trial that assesses inhaled nitric oxide as a treatment for patients with mild to moderate cases of COVID-19.
This is an international study testing using inhaled nitric oxide to improve outcomes for COVID-19 patients with severely damaged lungs; using gas to effectively “kill” corona virus in the lungs and improve delivery of oxygen to injured tissues. Inhaled nitric oxide had previously been suggested to decrease original SARS-CoV infectivity over a decade ago but its effect on SARS-CoV2 remains unknown.
This investigative therapy uses convalescent plasma from individuals who have recovered from COVID-19. It is possible convalescent plasma contains antibodies to SARS-CoV-2 (COVID-19) and might be effective against the infection. Use of convalescent plasma has been studied in outbreaks of other respiratory infections, including the 2009 H1N1 influenza virus pandemic, 2004 SRS-CoV-1 epidemic, and the 2012 MERS-CoV epidemic.
- LSU Health Shreveport Becomes Site for Additional Nitric Oxide Clinical Trial
- LSU Health Shreveport among the first in US to offer inhaled nitric oxide clinical trial for COVID-19 patients
- Health care professionals with LSU Health Shreveport, Ochsner LSU Health Shreveport and LifeShare Blood Center provide first COVID-19 convalescent plasma therapy in Louisiana
“We know a lot of these things work, we just don’t know when they work the best. And that’s what we’re trying to figure out really right now is when, how much and where. And that’s the confusing part of this whole disease. It’s nothing like we’ve ever seen, nothing like medicine has ever seen,” Dr. Keith Scott said.
“We will take their blood and run it through and siphon off the plasma, the plasma will have the antibodies and the antibodies will be administered to critically ill patients,” says LSUHS Chancellor Ghali.
“What we’re so excited about is this, it’s FDA approved. Almost any hospital of any size already has a ventilator, already has the gas and if this is something that does work it could start being applied immediately,” said LSUHS Professor, Keith Scott, MD.
For the majority of the first month of the outbreak in the State of Louisiana, Caddo Parish and Shreveport led the way in completed tests. That trend has now been joined by the way that LSU Health Shreveport is attacking the virus in the effort to defeat COVID-19.