A. Wayne Orr, PhD

Faculty Information

Professor and Director of the Research Division for Pathology and Translational Pathobiology, Director of the Center for Cardiovascular Diseases and Sciences

Contact Information

Work Phone

Other Information

Growing up in Arkansas, Dr. Orr earned his bachelor’s degree in Biology from Hendrix College (Conway, AR) in 1998. In 2002, he received his PhD in Cellular and Molecular Pathology from the University of Alabama at Birmingham, followed by Post-Doctoral training within the Cardiovascular Research Center at the University of Virginia. Dr. Orr joined the Department of Pathology at the LSU Health Shreveport in 2007, quickly rising through the ranks from Assistant Professor to Full Professor in 2017. Dr. A. Wayne Orr was appointed as Director of the Pathology Research Division in December 2016 and Director of the Center for Cardiovascular Disease and Sciences in August 2017. Dr. Orr runs an internationally renowned research laboratory and is the first investigator at LSU Health Shreveport to hold three concurrent National Institute of Health R01 grants. Dr. Orr’s research seeks to understand how the local microenvironment affects vascular cell signaling during pathological processes such as atherosclerosis, angiogenesis, and ischemia-reperfusion injury. Work from his group has identified a critical role for the extracellular matrix in the regulation of vascular cell function, characterizing novel signaling mechanisms and identifying specific receptors involved in this response. Dr. Orr is a long-time member of the American Diabetes Association (ADA), American Heart Association (AHA), and North American Vascular Biology Association (NAVBO). He currently serves on the leadership Council for NAVBO and the Leadership Committee for the Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) Council of the AHA, and he is the Chair of the ATVB Membership and Communications Committee. While previously serving on AHA grant review committees, Dr. Orr currently serves on the grant review committee for the ADA and as a charter member of the Vascular Cell and Molecular Biology study section in the Center for Scientific Review at the National Institute of Health. In addition, Dr. Orr serves on the Editorial Board of scientific journals ATVB and American Journal of Pathology. Dr. Orr and his wife Stephanie currently reside in Benton with their two children Charlotte and William.