Clinical Trials

Active Studies

The primary objective is to compare the safety and efficacy of the PMX cartridge (Toraymyxin) based on mortality at 28 days in patients with septic shock and endotoxemia who are treated with standard medical care plus the use of the PMX cartridge, versus patients who receive standard medical care alone.

Read More about TIGRIS Trial

The objective of this multicenter prospective study is to collect urine samples to validate the NEPHROCLEARTM CCL14 Test in intensive care unit (ICU) patients with moderate to severe (Stage 2 or 3) acute kidney injury (AKI) as an aid in the risk assessment for developing persistent severe AKI (Stage 3 AKI lasting >72 hours) within 48 hours of patient assessment. The study is observational and will have no impact on the medical management of the subject.

Read More about AST-132 Diamond

Completed Studies

  • Cumberland Pharmaceuticals Inc. A Multi-center, Double-blind, Randomized, Controlled Study to Determine the Efficacy and Safety of a New Formulation of Acetylcysteine Injection.  PI Thomas Arnold
  • BTG International. Observational Study of Recovery from Copperhead Snake Envenomation. Thomas Arnold, MD
  • Bush S, Ruha A, Seifert S, Morgan D, Lewis B, Arnold T, Clark R, Meggs W, Toschlog E, Borron S, Haynes J, Figge G, Sollee D, Shirazi F, Wolk R, Quan D, Garcia-Ubbelohde W, Boyer L. A prospective, multicenter, double-blind, randomized, controlled, clinicaltrial comparing Crotalinae Equine lmmune F(ab')2 and Crotalidae Polyvalent lmmune Fab (ovine) for the treatment of US Crotalinae envenomation. Clinical Toxicology 0812014; 52(7):686-687. doi: 10.3109/15563650.2014.974263

Emergency Medicine Research