Harris Lab

Dr. Randa Eshaq, Post-Doctoral Fellow, was recently awarded the 2019 Allied Health Teaching Award. The award is presented annual to one student and one faculty/post-doc course instructor.

My research career has focused on the physiology and pathophysiology of the microcirculation, and in recent years, much of our work has been an investigation of the retinal microvascular complications of diabetes.  Our lab is currently funded with an NIH R01 entitled “Loss of the retinal glycocalyx in diabetes”, and we also have ongoing projects related to other retinal pathologies.

Techniques that we use in the laboratory include intravital microscopy, measurement of microvascular flow, computerized video analysis of microscope images, immunostaining of tissue sections, culturing of retinal microvascular endothelial cells, and western blotting.

Below is one of our images of the retinal vasculature (in green) and neuronal nuclei (in red).

Selected Publications

1. Eshaq RS and Harris NR. Loss of platelet endothelial cell adhesion molecule-1 (PECAM-1) in the diabetic retina: role of matrix metalloproteinases. IOVS 60: 748-760, 2019.
2. Leskova W, Peace H, Eshaq RS, Shrestha B, Pattillo CB, and Harris NR. Effect of diabetes and hyaluronidase on the retinal endothelial glycocalyx in mice. Experimental Eye Research 179: 125-131, 2019.
3. Eshaq RS, Aldalati, AMZ, Alexander JS, and Harris NR. Diabetic retinopathy: breaking the barrier. Pathophysiology 24: 229-241, 2017.
4. Eshaq RS, Wright WS and Harris NR. Oxygen delivery, consumption, and conversion to reactive oxygen species in experimental models of diabetic retinopathy. Redox Biology 2: 661-666, 2014.

Complete List of my Published Work in MyBibliography: LEARN MORE
 

Minsup Lee, Ph.D.

Randa Eshaq, Ph.D.

Wenli Leskova

Gaganpreet Kaur

Post-doctoral Fellows

While we are not currently recruiting Post-doctoral Fellows, quality candidates will always be considered.  To enquire about opportunities, contact Dr. Harris at nharr6@lsuhsc.edu.

Graduate Students

Graduate students interested in conducting research in the Harris lab should review the current laboratory research directions and contact Dr. Harris at nharr6@lsuhsc.edu.

Undergraduate Research Assistants

We are not currently hiring any additional undergraduates. However, positions can become available during the summer.

Medical Students, Residents, and Fellows

The Harris laboratory has a number of research projects available for any Medical Students, Residents, and Fellows. Those interested should contact Dr. Harris at nharr6@lsuhsc.edu for more information.