Congratulations Sahar! Sahar Shekoohi, a member of the Witt lab, graduated with a PhD in May of 2021.
Sahar published a comprehensive characterization of SK-Mel-28, a melanoma cell line, with the gene SNCA knocked out. SNCA codes for the Parkinson’s disease-associated protein alpha-synuclein.
Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth. Shekoohi, S., Rajasekaran, S., Patel, P., Yang, S., Liu, W., Huang, S., Yu, X and Witt, S.N. Scientific Reports 2021 Mar 4;11(1):5267. doi: 10.1038/s41598-021-84443-y
Sahar is currently a postdoctoral fellow in the Department of Anesthesiology at LSU Health Shreveport.