Kevin S. Murnane, PhD, Associate Professor of Pharmacology, Toxicology and Neuroscience; Associate Professor of Psychiatry and Behavioral Medicine; and Director of Basic Science Research for Louisiana Addiction Research Center (LARC) was awarded a National Institute of Health (NIH) federal grant from the National Institute of Neurological Disorders and Stroke for $2.6 million dollars, funded over 5 years. The collaborative extramural research brings together experts from LSU Health Shreveport, Emory University, Mercer University and Morehouse School of Medicine. The research project entitled, “Exploring the Role of Oxytocin in the Regulation of Neuronal Excitability,” is focused on form of catastrophic childhood epilepsy called Dravet syndrome.
In this newly funded research, scientists will examine whether oxytocin can curb spontaneous seizures, behavioral abnormalities, and neuronal hyperexcitability. The long-term goals are to better understand the mechanisms by which neuropeptides regulate neuronal excitability, and to develop safe and effective approaches for the brain delivery of neuropeptides for the treatment of epilepsy and other brain disorders.
Learn more about Dr. Murnane's work on the Murnane Lab.