The Gross lab received a three year, $537,600 grant from NIGMS entitled, “Chromosomal Conformation and Nuclear Organization of Heat Shock Protein Genes.” The project focuses on the mechanism by which a DNA-binding protein, Heat Shock Factor 1 (HSF1), sculpts the three-dimensional architecture of the yeast genome. HSF1 is conserved from yeast to human and plays key roles in both neurodegeneration and cancer. This grant began on 1 May 2018.